I am increasingly growing in my conviction that we need an adjunct to the EPA’s Whole Effluent Toxicity (WET) Test.

I suggested that electrophysiological methods applied to the respiratory epithelia of the standard WET test organism, the Fathead Minnow, Pimephales promelas, as well as for mussels.  Electrophysiological techniques can be adapted for any living tissue.  I would like to see the addition of Amphioxus (Lancelet, or Branchiostoma spp.) with potential for chemoreceptive responses, epidermal responses and both behavioral and fictive approach & withdrawal responses.

I see accumulating support for this perspective:

https://www.the-scientist.com/?articles.view/articleNo/52106/title/BPA-Exposure-Alters-Behavior-and-Brain-Development-in-Mice–Study/

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